INNOVATIVE GENOME ANALYSIS

INNOVATIVE GENOME ANALYSIS

At Micar21 Ltd, we are helping usher in the new era of personalized medicine by enabling a fundamental change in healthcare with customized treatments and data-driven insights tailored to the individual.

At the heart of personalized medicine, DNA sequencing technology is advancing at an even more rapid pace than the cell phone revolution. By decreasing cost and increasing speed for the analysis of whole genome sequence (WGS) data, our technology platform makes it easier to discover links between DNA sequence variations and human diseases.

In particular, we bring to ordinary people advanced information obtained by high-end technology. Based on a DNA test, we can provide significant information – at a high level of confidence – about how an identified mutation alters protein structure and functions, whether it is disease-causing and whether existing drugs, if any, can influence a certain mutation.

All this information can be highly helpful for any physician in choosing an accurate corresponding treatment. Even more, if no approved treatment exists, we can propose an experimental one to physicians.

Each our client will receive a personal project.

DIFFERENCE BETWEEN CLASIC TECHNOLOGY AND OUR INNOVATIVE TECHNOLOGY

Our innovative technology

GPU Power

A graphics processing unit (GPU) in a combination with Compute Unified Device Architecture (CUDA) has provided in the recent few years completely new technology that allows a number of scientific calculations to be massively accelerated.

They provide an access to supercomputer scale performance without waiting for shared resources. GPU accelerators enable computational chemistry and biology researchers to push the boundaries of discovery.

... read more on Computational Chemistry in nvidia.com

Molecular Dynamics

MD simulations reproduce in a realistic way protein behavior in physiological conditions, revealing at a molecular level protein structure and, consequently, protein function.

Notably, this approach is one of the most advanced techniques allowing to differentiate compounds that are capable or not of binding to certain proteins. Nowadays, it is a valuable tool in many areas, including structural biology and in silico drug design.

Molecular Modeling

The field of molecular modeling comprise a vast number of scientific techniques. Docking and Pharmacophore in silico approaches are commonly used in discovery of novel bioactive ligands and in drug design.

By these powerful methods the screening of millions compounds is now possible predicting whether they can bind to certain proteins. Quantum chemistry is a branch of chemistry whose primary focus is the application of quantum mechanics in physical models predicting the chemical structure, physicochemical properties and etc.

Sctructural Biology

Structural biology is a branch of molecular biology, biochemistry, and biophysics concerned with the molecular structure of biological macromolecules, especially proteins and nucleic acids, how they acquire the structures they have, and how alterations in their structures affect their function.

Bio Informatics

Bioinformatics is an interdisciplinary field that develops methods and software tools for understanding biological data. As an interdisciplinary field of science, bioinformatics combines computer science, statistics, mathematics, and engineering to study and process biological data.

MICAR21 INNOVATIVE TECHNOLOGY

Our Technology is not just what it looks like and feels like. Technology is how it works revolutionally. - Dimitar Dimitrov